Drug interactions
Aripiprazole + Formoterol-mometasone
Severity: Moderate
Aripiprazole and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both formoterol and aripiprazole have been associated with QTc prolongation, so combined use may add modestly to arrhythmia risk, especially with high beta-agonist doses, hypokalemia or other risk factors. With inhaled formoterol at usual doses the effect is generally small.
What this interaction means in plain words
Aripiprazole and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aripiprazole belongs to Central Nervous System; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive pharmacodynamic effect on cardiac repolarization, with beta-agonist-induced hypokalemia potentially contributing.
What to do
Avoid exceeding recommended formoterol doses and correct hypokalemia or hypomagnesemia. Consider an ECG in patients with other QT risk factors or cardiac disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Aripiprazole and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both formoterol and aripiprazole have been associated with QTc prolongation, so combined use may add modestly to arrhythmia risk, especially with high beta-agonist doses, hypokalemia or other risk factors. With inhaled formoterol at usual doses the effect is generally small.
How serious is the interaction between Aripiprazole and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid exceeding recommended formoterol doses and correct hypokalemia or hypomagnesemia. Consider an ECG in patients with other QT risk factors or cardiac disease.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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