Drug interactions
Aripiprazole + Glycopyrronium
Severity: Minor
Aripiprazole and Glycopyrronium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aripiprazole has weak anticholinergic activity, so additive effects with glycopyrronium are possible but typically mild. Dry mouth or constipation may be slightly increased.
What this interaction means in plain words
Aripiprazole and Glycopyrronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aripiprazole belongs to Central Nervous System; Glycopyrronium belongs to Respiratory.
Why it happens
Weak additive antimuscarinic effects.
What to do
No routine change is needed; monitor for constipation or urinary retention in susceptible patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glycopyrronium
- Clozapine + Glycopyrronium Major
- Glycopyrronium + Potassium chloride Major
- Abobotulinumtoxina + Glycopyrronium Moderate
- Aclidinium + Glycopyrronium Moderate
- Amantadine + Glycopyrronium Moderate
- Amitriptyline + Glycopyrronium Moderate
Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Glycopyrronium?
MediHelp rates the interaction as minor. Aripiprazole and Glycopyrronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aripiprazole has weak anticholinergic activity, so additive effects with glycopyrronium are possible but typically mild. Dry mouth or constipation may be slightly increased.
How serious is the interaction between Aripiprazole and Glycopyrronium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor for constipation or urinary retention in susceptible patients.
What other medicines interact with Glycopyrronium?
MediHelp also lists interactions of Glycopyrronium with, for example, Clozapine, Potassium chloride, Abobotulinumtoxina. The full list is on the Glycopyrronium page.
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