Drug interactions
Aripiprazole + Vardenafil
Severity: Minor
Aripiprazole and Vardenafil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vardenafil can modestly prolong the QT interval, and aripiprazole has minimal QT effect, so additive risk is small. Clinical significance is mainly in patients with other QT risk factors.
What this interaction means in plain words
Aripiprazole and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aripiprazole belongs to Central Nervous System; Vardenafil belongs to Genitourinary.
Why it happens
Possible small additive QT prolongation; aripiprazole's QT effect is minimal.
What to do
No routine action is needed; correct electrolyte abnormalities and consider an ECG if other QT-prolonging drugs or risk factors are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vardenafil
- Amyl nitrite + Vardenafil Contraindicated
- Glyceryl trinitrate pr + Vardenafil Contraindicated
- Isosorbide dinitrate + Vardenafil Contraindicated
- Isosorbide mononitrate + Vardenafil Contraindicated
- Nicorandil + Vardenafil Contraindicated
- Nitroglycerin po + Vardenafil Contraindicated
Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Vardenafil?
MediHelp rates the interaction as minor. Aripiprazole and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vardenafil can modestly prolong the QT interval, and aripiprazole has minimal QT effect, so additive risk is small. Clinical significance is mainly in patients with other QT risk factors.
How serious is the interaction between Aripiprazole and Vardenafil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; correct electrolyte abnormalities and consider an ECG if other QT-prolonging drugs or risk factors are present.
What other medicines interact with Vardenafil?
MediHelp also lists interactions of Vardenafil with, for example, Amyl nitrite, Glyceryl trinitrate pr, Isosorbide dinitrate. The full list is on the Vardenafil page.
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