Drug interactions
Armodafinil + Griseofulvin
Severity: Minor
Armodafinil and Griseofulvin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin may modestly lower armodafinil concentrations. The wakefulness-promoting effect could be reduced.
What this interaction means in plain words
Armodafinil and Griseofulvin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Griseofulvin belongs to Anti Fungals.
Why it happens
Griseofulvin is a weak CYP3A4 inducer, increasing armodafinil metabolism.
What to do
Monitor for reduced armodafinil efficacy and increase the dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Griseofulvin
Other interactions of Armodafinil
Frequently asked questions
Can I take Armodafinil with Griseofulvin?
MediHelp rates the interaction as minor. Armodafinil and Griseofulvin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin may modestly lower armodafinil concentrations. The wakefulness-promoting effect could be reduced.
How serious is the interaction between Armodafinil and Griseofulvin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced armodafinil efficacy and increase the dose if needed.
What other medicines interact with Griseofulvin?
MediHelp also lists interactions of Griseofulvin with, for example, Cyclosporin, Desogestrel-ethinyl estradiol, Dienogest / estradiol valerate. The full list is on the Griseofulvin page.
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