Drug interactions
Armodafinil + Isradipine
Severity: Minor
Armodafinil and Isradipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Armodafinil is a weak CYP3A4 inducer and may reduce exposure to isradipine, a CYP3A4 substrate with extensive first-pass metabolism. This could diminish blood pressure control.
What this interaction means in plain words
Armodafinil and Isradipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Armodafinil weakly induces CYP3A4, increasing isradipine metabolism.
What to do
Monitor blood pressure after starting or stopping armodafinil and adjust the isradipine dose if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Armodafinil
Frequently asked questions
Can I take Armodafinil with Isradipine?
MediHelp rates the interaction as minor. Armodafinil and Isradipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Armodafinil is a weak CYP3A4 inducer and may reduce exposure to isradipine, a CYP3A4 substrate with extensive first-pass metabolism. This could diminish blood pressure control.
How serious is the interaction between Armodafinil and Isradipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure after starting or stopping armodafinil and adjust the isradipine dose if control changes.
What other medicines interact with Armodafinil?
MediHelp also lists interactions of Armodafinil with, for example, Avapritinib, Elacestrant, Elbasvir / grazoprevir. The full list is on the Armodafinil page.
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