Drug interactions
Armodafinil + Lansoprazole
Severity: Minor
Armodafinil and Lansoprazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Armodafinil inhibits CYP2C19 to a limited degree and can induce CYP3A4, so lansoprazole exposure could shift slightly in either direction. The net effect is small and rarely clinically important.
What this interaction means in plain words
Armodafinil and Lansoprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Lansoprazole belongs to Gastrointestinal Tract.
Why it happens
Armodafinil weakly inhibits CYP2C19 and induces CYP3A4, both of which contribute to lansoprazole metabolism.
What to do
No routine adjustment is needed; reassess acid-suppression response if symptoms change.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lansoprazole
- Lansoprazole + Mavacamten Contraindicated
- Lansoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Lansoprazole Major
- Atazanavir + Lansoprazole Major
- Dacomitinib + Lansoprazole Major
- Dasatinib + Lansoprazole Major
Other interactions of Armodafinil
Frequently asked questions
Can I take Armodafinil with Lansoprazole?
MediHelp rates the interaction as minor. Armodafinil and Lansoprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Armodafinil inhibits CYP2C19 to a limited degree and can induce CYP3A4, so lansoprazole exposure could shift slightly in either direction. The net effect is small and rarely clinically important.
How serious is the interaction between Armodafinil and Lansoprazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; reassess acid-suppression response if symptoms change.
What other medicines interact with Lansoprazole?
MediHelp also lists interactions of Lansoprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Lansoprazole page.
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