Drug interactions
Armodafinil + Theophylline
Severity: Minor
Armodafinil and Theophylline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Armodafinil is a weak inducer of CYP enzymes and might slightly lower theophylline levels. The clinical effect is expected to be small.
What this interaction means in plain words
Armodafinil and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Theophylline belongs to Respiratory.
Why it happens
Weak induction of CYP1A2 and CYP3A4 may modestly increase theophylline clearance.
What to do
No empirical dose change is needed; check theophylline levels if the response to therapy declines.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Theophylline
- Riociguat + Theophylline Contraindicated
- Adenosine + Theophylline Major
- Apalutamide + Theophylline Major
- Bupropion + Theophylline Major
- Carvedilol + Theophylline Major
- Cimetidine + Theophylline Major
Other interactions of Armodafinil
Frequently asked questions
Can I take Armodafinil with Theophylline?
MediHelp rates the interaction as minor. Armodafinil and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Armodafinil is a weak inducer of CYP enzymes and might slightly lower theophylline levels. The clinical effect is expected to be small.
How serious is the interaction between Armodafinil and Theophylline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empirical dose change is needed; check theophylline levels if the response to therapy declines.
What other medicines interact with Theophylline?
MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.
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