Drug interactions
Armodafinil + Triclofos
Severity: Minor
Armodafinil and Triclofos: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclofos is a sedative-hypnotic, while armodafinil is a wakefulness-promoting agent, so their effects oppose one another. Sedation from triclofos may be reduced, and armodafinil's benefit may be blunted. The net effect is unpredictable.
What this interaction means in plain words
Armodafinil and Triclofos have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing pharmacodynamic effects on CNS arousal; no pharmacokinetic mechanism is established.
What to do
Avoid using armodafinil to counteract triclofos sedation. Reassess the need for the hypnotic if both are prescribed and monitor sleep and alertness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Armodafinil and Triclofos, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Armodafinil
Frequently asked questions
Can I take Armodafinil with Triclofos?
MediHelp rates the interaction as minor. Armodafinil and Triclofos have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Triclofos is a sedative-hypnotic, while armodafinil is a wakefulness-promoting agent, so their effects oppose one another. Sedation from triclofos may be reduced, and armodafinil's benefit may be blunted. The net effect is unpredictable.
How serious is the interaction between Armodafinil and Triclofos?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using armodafinil to counteract triclofos sedation. Reassess the need for the hypnotic if both are prescribed and monitor sleep and alertness.
What other medicines interact with Armodafinil?
MediHelp also lists interactions of Armodafinil with, for example, Avapritinib, Elacestrant, Elbasvir / grazoprevir. The full list is on the Armodafinil page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
