Drug interactions
Artemether + Goserelin
Severity: Moderate
Artemether and Goserelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Artemether has a potential to prolong the QT interval, and goserelin may add to this through androgen deprivation. The combination may increase arrhythmia risk, particularly in patients with other risk factors.
What this interaction means in plain words
Artemether and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation from androgen deprivation (goserelin) and artemether effects on cardiac repolarization.
What to do
Check a baseline ECG and correct electrolyte disturbances. Monitor the QTc during treatment in patients with cardiac risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Goserelin
Frequently asked questions
Can I take Artemether with Goserelin?
MediHelp rates the interaction as moderate. Artemether and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Artemether has a potential to prolong the QT interval, and goserelin may add to this through androgen deprivation. The combination may increase arrhythmia risk, particularly in patients with other risk factors.
How serious is the interaction between Artemether and Goserelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check a baseline ECG and correct electrolyte disturbances. Monitor the QTc during treatment in patients with cardiac risk factors.
What other medicines interact with Goserelin?
MediHelp also lists interactions of Goserelin with, for example, Amisulpride, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Goserelin page.
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