Drug interactions
Artemether / lumefantrine + Indacaterol
Severity: Moderate
Artemether / lumefantrine and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Artemether/lumefantrine can prolong the QT interval, and its labeling advises caution with other QT-prolonging drugs. Indacaterol may add QT effects and lower potassium. The combination raises the risk of ventricular arrhythmia, particularly with additional risk factors.
What this interaction means in plain words
Artemether / lumefantrine and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and possible beta-agonist-induced hypokalemia.
What to do
Obtain an ECG and check electrolytes if there are cardiac risk factors, and monitor for palpitations or syncope during treatment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Frequently asked questions
Can I take Artemether / lumefantrine with Indacaterol?
MediHelp rates the interaction as moderate. Artemether / lumefantrine and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Artemether/lumefantrine can prolong the QT interval, and its labeling advises caution with other QT-prolonging drugs. Indacaterol may add QT effects and lower potassium. The combination raises the risk of ventricular arrhythmia, particularly with additional risk factors.
How serious is the interaction between Artemether / lumefantrine and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain an ECG and check electrolytes if there are cardiac risk factors, and monitor for palpitations or syncope during treatment.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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