Drug interactions
Amisulpride + Indacaterol
Severity: Major
Amisulpride and Indacaterol: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amisulpride prolongs the QT interval in a dose-related way, and indacaterol may add to this through tachycardia and hypokalemia. The combination may increase the risk of torsades de pointes.
What this interaction means in plain words
Amisulpride and Indacaterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Indacaterol belongs to Respiratory.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia.
What to do
Monitor ECG and correct potassium and magnesium before and during co-therapy. Avoid if QTc is already prolonged.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Amisulpride and Indacaterol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Indacaterol
Other interactions of Amisulpride
- Amiodarone + Amisulpride Contraindicated
- Amisulpride + Arsenic trioxide Contraindicated
- Amisulpride + Disopyramide Contraindicated
- Amisulpride + Dofetilide Contraindicated
- Amisulpride + Droperidol Contraindicated
- Amisulpride + Ibutilide Contraindicated
Frequently asked questions
Can I take Amisulpride with Indacaterol?
MediHelp rates the interaction as major. Amisulpride and Indacaterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amisulpride prolongs the QT interval in a dose-related way, and indacaterol may add to this through tachycardia and hypokalemia. The combination may increase the risk of torsades de pointes.
How serious is the interaction between Amisulpride and Indacaterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and correct potassium and magnesium before and during co-therapy. Avoid if QTc is already prolonged.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amitriptyline. The full list is on the Indacaterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
