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Drug interactions

Astragalus + Infliximab

Severity: Minor

Astragalus and Infliximab: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Astragalus is claimed to have immune-stimulating properties that could theoretically oppose infliximab's immunosuppression. The clinical effect is uncertain and could be loss of disease control or flares.

What this interaction means in plain words

Astragalus and Infliximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical pharmacodynamic opposition from immunostimulatory herbal constituents; not well established.

What to do

Advise patients to avoid astragalus while on infliximab. Monitor disease activity if the herb is used.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Astragalus with Infliximab?

MediHelp rates the interaction as minor. Astragalus and Infliximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Astragalus is claimed to have immune-stimulating properties that could theoretically oppose infliximab's immunosuppression. The clinical effect is uncertain and could be loss of disease control or flares.

How serious is the interaction between Astragalus and Infliximab?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid astragalus while on infliximab. Monitor disease activity if the herb is used.

What other medicines interact with Infliximab?

MediHelp also lists interactions of Infliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Infliximab page.

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