Drug reference
infliximab
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (TNF-alpha Inhibitors)
Mechanism of action
Recombinant humanized monoclonal anti-TNF-alpha antibody; prevents synovial and intestinal inflammation.
Common side effects
- Upper respiratory tract infection
- Development of antinuclear antibodies
- Headache
- Infection
- Abdominal pain
Contraindications
- Active serious infections Documented hypersensitivity Doses >5 mg/kg in patients with moderate-to-severe heart failure (NYHA Class III/IV)
Known interactions (5)
- infliximab + measles mumps and rubella vaccine Contraindicated
- abatacept + infliximab Major
- infliximab + upadacitinib Major
- hepatitis a vaccine inactivated + infliximab Moderate
- infliximab + pneumococcal vaccine 13-valent Moderate
Related conditions
Frequently asked questions
What drug class is infliximab?
infliximab belongs to: Musculoskeletal.
How does infliximab work?
Recombinant humanized monoclonal anti-TNF-alpha antibody; prevents synovial and intestinal inflammation.
What are the common side effects of infliximab?
Upper respiratory tract infection, Development of antinuclear antibodies, Headache, Infection, Abdominal pain
Which drugs interact with infliximab?
measles mumps and rubella vaccine, abatacept, upadacitinib, hepatitis a vaccine inactivated, pneumococcal vaccine 13-valent
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.