Drug interactions
Astragalus + Temsirolimus
Severity: Minor
Astragalus and Temsirolimus: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Astragalus is reputed to stimulate immune function, which could oppose the immunosuppressive action of temsirolimus. The clinical effect is uncertain and poorly characterized.
What this interaction means in plain words
Astragalus and Temsirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic opposition between herbal immunostimulant activity and mTOR-mediated immunosuppression; not well established.
What to do
Advise patients to avoid astragalus supplements during temsirolimus therapy where possible. Monitor for infection or unexpected changes in treatment response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Temsirolimus
- Bcg vaccine live + Temsirolimus Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Temsirolimus Contraindicated
- Measles mumps and rubella vaccine live + Temsirolimus Contraindicated
- Measles mumps rubella and varicella vaccine live + Temsirolimus Contraindicated
- Measles vaccine + Temsirolimus Contraindicated
- Rotavirus oral vaccine live + Temsirolimus Contraindicated
Frequently asked questions
Can I take Astragalus with Temsirolimus?
MediHelp rates the interaction as minor. Astragalus and Temsirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Astragalus is reputed to stimulate immune function, which could oppose the immunosuppressive action of temsirolimus. The clinical effect is uncertain and poorly characterized.
How serious is the interaction between Astragalus and Temsirolimus?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid astragalus supplements during temsirolimus therapy where possible. Monitor for infection or unexpected changes in treatment response.
What other medicines interact with Temsirolimus?
MediHelp also lists interactions of Temsirolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Temsirolimus page.
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