Drug interactions
Atazanavir + Dapagliflozin-metformin
Severity: Minor
Atazanavir and Dapagliflozin-metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Protease inhibitors can induce insulin resistance and hyperglycemia, though atazanavir has relatively less metabolic effect. This may blunt antidiabetic therapy in some patients.
What this interaction means in plain words
Atazanavir and Dapagliflozin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atazanavir belongs to Anti Virals; Dapagliflozin-metformin belongs to Endocrine.
Why it happens
Protease inhibitors may impair insulin sensitivity and glucose uptake, opposing glucose-lowering therapy.
What to do
Monitor blood glucose after starting atazanavir and adjust the antidiabetic regimen if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapagliflozin-metformin
Other interactions of Atazanavir
- Alfuzosin + Atazanavir Contraindicated
- Atazanavir + Avanafil Contraindicated
- Atazanavir + Dronedarone Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Atazanavir + Eplerenone Contraindicated
- Atazanavir + Ergotamine Contraindicated
Frequently asked questions
Can I take Atazanavir with Dapagliflozin-metformin?
MediHelp rates the interaction as minor. Atazanavir and Dapagliflozin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Protease inhibitors can induce insulin resistance and hyperglycemia, though atazanavir has relatively less metabolic effect. This may blunt antidiabetic therapy in some patients.
How serious is the interaction between Atazanavir and Dapagliflozin-metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting atazanavir and adjust the antidiabetic regimen if control worsens.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
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