Drug interactions
Atazanavir + Nadolol
Severity: Moderate
Atazanavir and Nadolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atazanavir can prolong the PR interval, and combining it with a beta-blocker may add to AV conduction delay and bradycardia. Hypotension may also occur.
What this interaction means in plain words
Atazanavir and Nadolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atazanavir belongs to Anti Virals; Nadolol belongs to Cardiovascular.
Why it happens
Additive negative dromotropic effects on AV nodal conduction.
What to do
Monitor heart rate, blood pressure and ECG PR interval, and reduce the nadolol dose if bradycardia or conduction delay develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nadolol
Other interactions of Atazanavir
- Alfuzosin + Atazanavir Contraindicated
- Atazanavir + Avanafil Contraindicated
- Atazanavir + Dronedarone Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Atazanavir + Eplerenone Contraindicated
- Atazanavir + Ergotamine Contraindicated
Frequently asked questions
Can I take Atazanavir with Nadolol?
MediHelp rates the interaction as moderate. Atazanavir and Nadolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atazanavir can prolong the PR interval, and combining it with a beta-blocker may add to AV conduction delay and bradycardia. Hypotension may also occur.
How serious is the interaction between Atazanavir and Nadolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and ECG PR interval, and reduce the nadolol dose if bradycardia or conduction delay develops.
What other medicines interact with Nadolol?
MediHelp also lists interactions of Nadolol with, for example, Acebutolol, Adrenaline-articaine, Amifostine. The full list is on the Nadolol page.
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