Drug interactions
Atazanavir + Zidovudine
Severity: Minor
Atazanavir and Zidovudine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both are used in HIV treatment, and immune reconstitution inflammatory syndrome may appear after starting effective therapy. This reflects recovering immunity rather than a pharmacological interaction between the two drugs.
What this interaction means in plain words
Atazanavir and Zidovudine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atazanavir belongs to Anti Virals; Zidovudine belongs to Anti Virals.
Why it happens
Immune reconstitution results from recovery of immune function with antiretroviral therapy rather than a specific drug interaction.
What to do
Monitor for new inflammatory or opportunistic infection symptoms after initiating therapy. Treat the underlying infection while generally continuing antiretrovirals.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Zidovudine
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Zidovudine Contraindicated
- Stavudine + Zidovudine Contraindicated
- Atidarsagene autotemcel + Zidovudine Major
- Betibeglogene autotemcel + Zidovudine Major
- Carboplatin + Zidovudine Major
- Cisplatin + Zidovudine Major
Other interactions of Atazanavir
- Alfuzosin + Atazanavir Contraindicated
- Atazanavir + Avanafil Contraindicated
- Atazanavir + Dronedarone Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Atazanavir + Eplerenone Contraindicated
- Atazanavir + Ergotamine Contraindicated
Frequently asked questions
Can I take Atazanavir with Zidovudine?
MediHelp rates the interaction as minor. Atazanavir and Zidovudine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both are used in HIV treatment, and immune reconstitution inflammatory syndrome may appear after starting effective therapy. This reflects recovering immunity rather than a pharmacological interaction between the two drugs.
How serious is the interaction between Atazanavir and Zidovudine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for new inflammatory or opportunistic infection symptoms after initiating therapy. Treat the underlying infection while generally continuing antiretrovirals.
What other medicines interact with Zidovudine?
MediHelp also lists interactions of Zidovudine with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Stavudine, Atidarsagene autotemcel. The full list is on the Zidovudine page.
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