Drug interactions
Atenolol + Dasiglucagon
Severity: Moderate
Atenolol and Dasiglucagon: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Beta blockers may blunt the glycemic and catecholamine-mediated effects of glucagon agonists and can lead to transient rises in pulse and blood pressure from unopposed alpha stimulation. Response to treatment of severe hypoglycemia may be reduced.
What this interaction means in plain words
Atenolol and Dasiglucagon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Dasiglucagon belongs to Endocrine.
Why it happens
Beta blockade antagonizes catecholamine release triggered by dasiglucagon; the exact mechanism is incompletely characterized.
What to do
Monitor blood glucose, heart rate and blood pressure after dasiglucagon and be ready to give glucose or other measures if the response is inadequate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Other interactions of Dasiglucagon
- Dasiglucagon + Esmolol Moderate
- Dasiglucagon + Propranolol Moderate
- Dasiglucagon + Timolol Moderate
- Dasiglucagon + Warfarin Moderate
- Atenolol-chlorthalidone + Dasiglucagon Minor
- Betaxolol + Dasiglucagon Minor
Frequently asked questions
Can I take Atenolol with Dasiglucagon?
MediHelp rates the interaction as moderate. Atenolol and Dasiglucagon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Beta blockers may blunt the glycemic and catecholamine-mediated effects of glucagon agonists and can lead to transient rises in pulse and blood pressure from unopposed alpha stimulation. Response to treatment of severe hypoglycemia may be reduced.
How serious is the interaction between Atenolol and Dasiglucagon?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose, heart rate and blood pressure after dasiglucagon and be ready to give glucose or other measures if the response is inadequate.
What other medicines interact with Atenolol?
MediHelp also lists interactions of Atenolol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Atenolol page.
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