Drug interactions
Atenolol + Indacaterol
Severity: Moderate
Atenolol and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Beta-blockers antagonize the bronchodilating effect of beta-2 agonists and may trigger bronchospasm in patients with airway disease. Atenolol is cardioselective, which lowers but does not remove this risk at higher doses.
What this interaction means in plain words
Atenolol and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Indacaterol belongs to Respiratory.
Why it happens
Pharmacodynamic antagonism at beta-adrenergic receptors; cardioselectivity is dose dependent.
What to do
Use beta-blockers only when clearly indicated in COPD or asthma, preferring a cardioselective agent at the lowest effective dose, and monitor respiratory function and symptoms.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Atenolol with Indacaterol?
MediHelp rates the interaction as moderate. Atenolol and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Beta-blockers antagonize the bronchodilating effect of beta-2 agonists and may trigger bronchospasm in patients with airway disease. Atenolol is cardioselective, which lowers but does not remove this risk at higher doses.
How serious is the interaction between Atenolol and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use beta-blockers only when clearly indicated in COPD or asthma, preferring a cardioselective agent at the lowest effective dose, and monitor respiratory function and symptoms.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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