Drug interactions
Atomoxetine + Dopamine
Severity: Moderate
Atomoxetine and Dopamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atomoxetine can raise blood pressure and heart rate, and dopamine is a vasopressor with the same effects. Together they may cause excessive hypertension or tachycardia.
What this interaction means in plain words
Atomoxetine and Dopamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Dopamine belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic sympathomimetic effects on blood pressure and heart rate.
What to do
Monitor blood pressure and heart rate closely and titrate the dopamine infusion to the response. Consider holding atomoxetine in acutely ill patients on vasopressors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dopamine
- Dihydroergotamine intranasal + Dopamine Contraindicated
- Dihydroergotamine + Dopamine Contraindicated
- Dopamine + Promethazine Contraindicated
- Dopamine + Selegiline transdermal Contraindicated
- Amitriptyline + Dopamine Major
- Clomipramine + Dopamine Major
Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Dopamine?
MediHelp rates the interaction as moderate. Atomoxetine and Dopamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atomoxetine can raise blood pressure and heart rate, and dopamine is a vasopressor with the same effects. Together they may cause excessive hypertension or tachycardia.
How serious is the interaction between Atomoxetine and Dopamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate closely and titrate the dopamine infusion to the response. Consider holding atomoxetine in acutely ill patients on vasopressors.
What other medicines interact with Dopamine?
MediHelp also lists interactions of Dopamine with, for example, Dihydroergotamine intranasal, Dihydroergotamine, Promethazine. The full list is on the Dopamine page.
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