Drug interactions
Atomoxetine + Goserelin
Severity: Moderate
Atomoxetine and Goserelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgen deprivation therapy with goserelin may prolong the QT interval, and atomoxetine may add modest QT and heart rate effects. The risk is mainly relevant in patients with existing cardiac disease or electrolyte disturbance.
What this interaction means in plain words
Atomoxetine and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Goserelin belongs to Endocrine.
Why it happens
Additive QT prolongation (pharmacodynamic).
What to do
Check baseline ECG and electrolytes in patients with cardiac risk factors and monitor periodically. Consider alternatives if QT prolongation develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Other interactions of Goserelin
Frequently asked questions
Can I take Atomoxetine with Goserelin?
MediHelp rates the interaction as moderate. Atomoxetine and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Androgen deprivation therapy with goserelin may prolong the QT interval, and atomoxetine may add modest QT and heart rate effects. The risk is mainly relevant in patients with existing cardiac disease or electrolyte disturbance.
How serious is the interaction between Atomoxetine and Goserelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes in patients with cardiac risk factors and monitor periodically. Consider alternatives if QT prolongation develops.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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