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Drug interactions

Atomoxetine + Triclabendazole

Severity: Moderate

Atomoxetine and Triclabendazole: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Triclabendazole can prolong the QT interval, so combining it with atomoxetine may increase the risk of arrhythmia. The exposure is brief but still relevant in patients with other risk factors.

What this interaction means in plain words

Atomoxetine and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Atomoxetine belongs to Central Nervous System; Triclabendazole belongs to Anti Parasitic.

Evidence level: Low

Why it happens

Additive QTc prolongation.

What to do

Consider an ECG in patients with cardiac risk factors or electrolyte abnormalities, and correct these before dosing.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Atomoxetine with Triclabendazole?

MediHelp rates the interaction as moderate. Atomoxetine and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triclabendazole can prolong the QT interval, so combining it with atomoxetine may increase the risk of arrhythmia. The exposure is brief but still relevant in patients with other risk factors.

How serious is the interaction between Atomoxetine and Triclabendazole?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider an ECG in patients with cardiac risk factors or electrolyte abnormalities, and correct these before dosing.

What other medicines interact with Atomoxetine?

MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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