Drug interactions
Atorvastatin + Flibanserin
Severity: Minor
Atorvastatin and Flibanserin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atorvastatin is a CYP3A4 substrate with at most weak inhibitory activity and is not an established inhibitor of flibanserin metabolism. Flibanserin is a weak P-gp inhibitor and could raise atorvastatin levels slightly. A clinically relevant interaction is unlikely.
What this interaction means in plain words
Atorvastatin and Flibanserin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atorvastatin belongs to Cardiovascular; Flibanserin belongs to Genitourinary.
Why it happens
Theoretical minor CYP3A4 or P-gp effects; not well established.
What to do
No routine adjustment is needed. Be alert for statin-related muscle symptoms and for dizziness with flibanserin.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flibanserin
- Atazanavir + Flibanserin Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Clarithromycin + Flibanserin Contraindicated
- Cobicistat + Flibanserin Contraindicated
- Conivaptan + Flibanserin Contraindicated
- Crizotinib + Flibanserin Contraindicated
Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Danazol Major
Frequently asked questions
Can I take Atorvastatin with Flibanserin?
MediHelp rates the interaction as minor. Atorvastatin and Flibanserin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atorvastatin is a CYP3A4 substrate with at most weak inhibitory activity and is not an established inhibitor of flibanserin metabolism. Flibanserin is a weak P-gp inhibitor and could raise atorvastatin levels slightly. A clinically relevant interaction is unlikely.
How serious is the interaction between Atorvastatin and Flibanserin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Be alert for statin-related muscle symptoms and for dizziness with flibanserin.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
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