Drug interactions
Atorvastatin + Oteseconazole
Severity: Moderate
Atorvastatin and Oteseconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oteseconazole inhibits BCRP and may raise atorvastatin exposure. This may increase the risk of myopathy.
What this interaction means in plain words
Atorvastatin and Oteseconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atorvastatin belongs to Cardiovascular; Oteseconazole belongs to Anti Fungals.
Why it happens
BCRP inhibition by oteseconazole increases atorvastatin bioavailability.
What to do
Use the lowest atorvastatin dose needed and monitor for muscle symptoms.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Cyclosporine Major
Other interactions of Oteseconazole
- Fluvastatin + Oteseconazole Moderate
- Glyburide-metformin + Oteseconazole Moderate
- Glyburide + Oteseconazole Moderate
- Irinotecan + Oteseconazole Moderate
- Lapatinib + Oteseconazole Moderate
- Leflunomide + Oteseconazole Moderate
Frequently asked questions
Can I take Atorvastatin with Oteseconazole?
MediHelp rates the interaction as moderate. Atorvastatin and Oteseconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oteseconazole inhibits BCRP and may raise atorvastatin exposure. This may increase the risk of myopathy.
How serious is the interaction between Atorvastatin and Oteseconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest atorvastatin dose needed and monitor for muscle symptoms.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
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