Drug interactions
Atropine + Umeclidinium-vilanterol
Severity: Moderate
Atropine and Umeclidinium-vilanterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atropine and umeclidinium are both antimuscarinic and their effects add together. This may cause dry mouth, tachycardia, urinary retention, constipation, blurred vision and raised intraocular pressure.
What this interaction means in plain words
Atropine and Umeclidinium-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atropine belongs to Miscellaneous; Umeclidinium-vilanterol belongs to Respiratory.
Why it happens
Additive antimuscarinic effects.
What to do
Monitor for anticholinergic adverse effects, especially in older patients or those with glaucoma or urinary retention. Reduce or stop one agent if effects occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Umeclidinium-vilanterol
Other interactions of Atropine
- Atropine + Eluxadoline Major
- Atropine + Henbane Major
- Atropine + Pramlintide Major
- Abobotulinumtoxina + Atropine Moderate
- Aclidinium + Atropine Moderate
- Amantadine + Atropine Moderate
Frequently asked questions
Can I take Atropine with Umeclidinium-vilanterol?
MediHelp rates the interaction as moderate. Atropine and Umeclidinium-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atropine and umeclidinium are both antimuscarinic and their effects add together. This may cause dry mouth, tachycardia, urinary retention, constipation, blurred vision and raised intraocular pressure.
How serious is the interaction between Atropine and Umeclidinium-vilanterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic adverse effects, especially in older patients or those with glaucoma or urinary retention. Reduce or stop one agent if effects occur.
What other medicines interact with Umeclidinium-vilanterol?
MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.
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