Drug interactions
Azilsartan-chlorthalidone + Nebivolol
Severity: Minor
Azilsartan-chlorthalidone and Nebivolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nebivolol added to an ARB and thiazide-like diuretic produces additive blood pressure lowering, which is often intentional but can cause hypotension or bradycardia. Effects on potassium are small and offsetting.
What this interaction means in plain words
Azilsartan-chlorthalidone and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azilsartan-chlorthalidone belongs to Cardiovascular; Nebivolol belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic antihypertensive effects with minor opposing effects on potassium.
What to do
Monitor blood pressure and heart rate and check serum potassium periodically. Adjust doses if symptomatic hypotension develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azilsartan-chlorthalidone
Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Azilsartan-chlorthalidone with Nebivolol?
MediHelp rates the interaction as minor. Azilsartan-chlorthalidone and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nebivolol added to an ARB and thiazide-like diuretic produces additive blood pressure lowering, which is often intentional but can cause hypotension or bradycardia. Effects on potassium are small and offsetting.
How serious is the interaction between Azilsartan-chlorthalidone and Nebivolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate and check serum potassium periodically. Adjust doses if symptomatic hypotension develops.
What other medicines interact with Azilsartan-chlorthalidone?
MediHelp also lists interactions of Azilsartan-chlorthalidone with, for example, Aliskiren, Sparsentan, Aceclofenac. The full list is on the Azilsartan-chlorthalidone page.
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