Drug interactions
Azithromycin + Bazedoxifene-conjugated estrogens
Severity: Minor
Azithromycin and Bazedoxifene-conjugated estrogens: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antibiotics were once thought to reduce estrogen recirculation by disturbing gut flora, but this is not convincingly shown for azithromycin. Any effect on conjugated estrogens is expected to be negligible, and this product is not a contraceptive.
What this interaction means in plain words
Azithromycin and Bazedoxifene-conjugated estrogens have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azithromycin belongs to Anti Bacterial; Bazedoxifene-conjugated estrogens belongs to Endocrine.
Why it happens
Theoretical reduction of enterohepatic estrogen recirculation through altered intestinal flora; not well established.
What to do
No change in therapy is needed; consider reassessing menopausal symptom control only if symptoms recur during prolonged antibiotic use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bazedoxifene-conjugated estrogens
- Anastrozole + Bazedoxifene-conjugated estrogens Contraindicated
- Bazedoxifene-conjugated estrogens + Ospemifene Contraindicated
- Antithrombin alfa + Bazedoxifene-conjugated estrogens Major
- Antithrombin iii + Bazedoxifene-conjugated estrogens Major
- Bazedoxifene-conjugated estrogens + Bemiparin Major
- Bazedoxifene-conjugated estrogens + Carbamazepine Major
Other interactions of Azithromycin
- Azithromycin + Cisapride Contraindicated
- Azithromycin + Domperidone Contraindicated
- Azithromycin + Dronedarone Contraindicated
- Azithromycin + Pimozide Contraindicated
- Azithromycin + Piperaquine Contraindicated
- Azithromycin + Thioridazine Contraindicated
Frequently asked questions
Can I take Azithromycin with Bazedoxifene-conjugated estrogens?
MediHelp rates the interaction as minor. Azithromycin and Bazedoxifene-conjugated estrogens have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antibiotics were once thought to reduce estrogen recirculation by disturbing gut flora, but this is not convincingly shown for azithromycin. Any effect on conjugated estrogens is expected to be negligible, and this product is not a contraceptive.
How serious is the interaction between Azithromycin and Bazedoxifene-conjugated estrogens?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change in therapy is needed; consider reassessing menopausal symptom control only if symptoms recur during prolonged antibiotic use.
What other medicines interact with Bazedoxifene-conjugated estrogens?
MediHelp also lists interactions of Bazedoxifene-conjugated estrogens with, for example, Anastrozole, Ospemifene, Antithrombin alfa. The full list is on the Bazedoxifene-conjugated estrogens page.
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