Drug interactions
Azithromycin + Pivmecillinam
Severity: Minor
Azithromycin and Pivmecillinam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azithromycin is bacteriostatic and may theoretically blunt the bactericidal effect of pivmecillinam. The clinical significance is unknown and the pair is rarely used together.
What this interaction means in plain words
Azithromycin and Pivmecillinam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azithromycin belongs to Anti Bacterial; Pivmecillinam belongs to Anti Bacterial.
Why it happens
Theoretical pharmacodynamic antagonism between a protein synthesis inhibitor and a cell-wall-active beta-lactam.
What to do
No specific action is needed. Monitor clinical response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azithromycin
- Azithromycin + Cisapride Contraindicated
- Azithromycin + Domperidone Contraindicated
- Azithromycin + Dronedarone Contraindicated
- Azithromycin + Pimozide Contraindicated
- Azithromycin + Piperaquine Contraindicated
- Azithromycin + Thioridazine Contraindicated
Other interactions of Pivmecillinam
- Doxycycline + Pivmecillinam Moderate
- Minocycline + Pivmecillinam Moderate
- Pivmecillinam + Probenecid Moderate
- Pivmecillinam + Tetracycline Moderate
- Acetylsalicylic acid + Pivmecillinam Minor
- Acyclovir + Pivmecillinam Minor
Frequently asked questions
Can I take Azithromycin with Pivmecillinam?
MediHelp rates the interaction as minor. Azithromycin and Pivmecillinam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Azithromycin is bacteriostatic and may theoretically blunt the bactericidal effect of pivmecillinam. The clinical significance is unknown and the pair is rarely used together.
How serious is the interaction between Azithromycin and Pivmecillinam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed. Monitor clinical response.
What other medicines interact with Azithromycin?
MediHelp also lists interactions of Azithromycin with, for example, Cisapride, Domperidone, Dronedarone. The full list is on the Azithromycin page.
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