Drug interactions
Balsalazide + Oxaprozin
Severity: Minor
Balsalazide and Oxaprozin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxaprozin is an acidic NSAID that could compete with balsalazide metabolites for renal tubular secretion. Any effect on exposure is likely small. NSAIDs may also aggravate colitis and renal function.
What this interaction means in plain words
Balsalazide and Oxaprozin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Balsalazide belongs to Gastrointestinal Tract; Oxaprozin belongs to Musculoskeletal.
Why it happens
Possible competition for renal tubular anionic secretion; this is largely theoretical.
What to do
No dose adjustment is needed; monitor renal function and GI symptoms with prolonged use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Balsalazide
Other interactions of Oxaprozin
- Ketorolac intranasal + Oxaprozin Contraindicated
- Ketorolac + Oxaprozin Contraindicated
- Aceclofenac + Oxaprozin Major
- Acemetacin + Oxaprozin Major
- Acetylsalicylic acid + Oxaprozin Major
- Alteplase + Oxaprozin Major
Frequently asked questions
Can I take Balsalazide with Oxaprozin?
MediHelp rates the interaction as minor. Balsalazide and Oxaprozin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oxaprozin is an acidic NSAID that could compete with balsalazide metabolites for renal tubular secretion. Any effect on exposure is likely small. NSAIDs may also aggravate colitis and renal function.
How serious is the interaction between Balsalazide and Oxaprozin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; monitor renal function and GI symptoms with prolonged use.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.
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