Drug interactions
Balsalazide + Pivmecillinam
Severity: Minor
Balsalazide and Pivmecillinam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Penicillins are renally secreted by organic anion transporters, and salicylate-type metabolites may compete for this pathway. Penicillin levels may rise slightly, though clinical impact is probably small.
What this interaction means in plain words
Balsalazide and Pivmecillinam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Balsalazide belongs to Gastrointestinal Tract; Pivmecillinam belongs to Anti Bacterial.
Why it happens
Competition for renal tubular organic anion secretion.
What to do
No routine adjustment is needed; monitor in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Balsalazide
Other interactions of Pivmecillinam
- Doxycycline + Pivmecillinam Moderate
- Minocycline + Pivmecillinam Moderate
- Pivmecillinam + Probenecid Moderate
- Pivmecillinam + Tetracycline Moderate
- Acetylsalicylic acid + Pivmecillinam Minor
- Acyclovir + Pivmecillinam Minor
Frequently asked questions
Can I take Balsalazide with Pivmecillinam?
MediHelp rates the interaction as minor. Balsalazide and Pivmecillinam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Penicillins are renally secreted by organic anion transporters, and salicylate-type metabolites may compete for this pathway. Penicillin levels may rise slightly, though clinical impact is probably small.
How serious is the interaction between Balsalazide and Pivmecillinam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; monitor in patients with renal impairment.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.
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