Drug interactions
Balsalazide + Warfarin
Severity: Minor
Balsalazide and Warfarin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Case reports have described altered INR in patients taking mesalamine-type drugs with warfarin, but the evidence is inconsistent. The effect is generally small.
What this interaction means in plain words
Balsalazide and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Balsalazide belongs to Gastrointestinal Tract; Warfarin belongs to Cardiovascular.
Why it happens
Mechanism not established.
What to do
Check INR after starting or stopping balsalazide and adjust warfarin dose accordingly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Balsalazide
Other interactions of Warfarin
- Defibrotide + Warfarin Contraindicated
- Ketorolac + Warfarin Contraindicated
- Abciximab + Warfarin Major
- Acetylsalicylic acid + Warfarin Major
- Adagrasib + Warfarin Major
- Amiodarone + Warfarin Major
Frequently asked questions
Can I take Balsalazide with Warfarin?
MediHelp rates the interaction as minor. Balsalazide and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Case reports have described altered INR in patients taking mesalamine-type drugs with warfarin, but the evidence is inconsistent. The effect is generally small.
How serious is the interaction between Balsalazide and Warfarin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR after starting or stopping balsalazide and adjust warfarin dose accordingly.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.
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