Drug interactions
Basiliximab + Tacrolimus
Severity: Minor
Basiliximab and Tacrolimus: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Basiliximab is routinely given with tacrolimus-based regimens as induction therapy in transplantation. Together they increase overall immunosuppression and infection risk, but this is the intended, standard use and is not a harmful interaction.
What this interaction means in plain words
Basiliximab and Tacrolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Basiliximab belongs to Miscellaneous; Tacrolimus belongs to Miscellaneous.
Why it happens
Complementary immunosuppression: basiliximab blocks the IL-2 receptor while tacrolimus inhibits calcineurin.
What to do
Use per transplant protocol and monitor for infection and tacrolimus trough levels.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tacrolimus
- Adenovirus types 4 and 7 live + Tacrolimus Contraindicated
- Bcg vaccine live + Tacrolimus Contraindicated
- Cidofovir + Tacrolimus Contraindicated
- Cyclosporin + Tacrolimus Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Tacrolimus Contraindicated
- Measles mumps and rubella vaccine live + Tacrolimus Contraindicated
Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Basiliximab with Tacrolimus?
MediHelp rates the interaction as minor. Basiliximab and Tacrolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Basiliximab is routinely given with tacrolimus-based regimens as induction therapy in transplantation. Together they increase overall immunosuppression and infection risk, but this is the intended, standard use and is not a harmful interaction.
How serious is the interaction between Basiliximab and Tacrolimus?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use per transplant protocol and monitor for infection and tacrolimus trough levels.
What other medicines interact with Tacrolimus?
MediHelp also lists interactions of Tacrolimus with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Cidofovir. The full list is on the Tacrolimus page.
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