Drug interactions
Bazedoxifene-conjugated estrogens + Folic acid
Severity: Minor
Bazedoxifene-conjugated estrogens and Folic acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral estrogens have been linked to modestly lower folate levels in some studies. The effect is small and rarely causes deficiency.
What this interaction means in plain words
Bazedoxifene-conjugated estrogens and Folic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bazedoxifene-conjugated estrogens belongs to Endocrine; Folic acid belongs to Miscellaneous.
Why it happens
Mechanism not established; possibly altered folate metabolism or distribution.
What to do
No action is required; assess folate status only if deficiency is suspected.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bazedoxifene-conjugated estrogens
- Anastrozole + Bazedoxifene-conjugated estrogens Contraindicated
- Bazedoxifene-conjugated estrogens + Ospemifene Contraindicated
- Antithrombin alfa + Bazedoxifene-conjugated estrogens Major
- Antithrombin iii + Bazedoxifene-conjugated estrogens Major
- Bazedoxifene-conjugated estrogens + Bemiparin Major
- Bazedoxifene-conjugated estrogens + Carbamazepine Major
Other interactions of Folic acid
- Ethotoin + Folic acid Moderate
- Folic acid + Fosphenytoin Moderate
- Folic acid + Glucarpidase Moderate
- Folic acid + Methotrexate Moderate
- Folic acid + Pafolacianine Moderate
- Folic acid + Phenobarbital Moderate
Frequently asked questions
Can I take Bazedoxifene-conjugated estrogens with Folic acid?
MediHelp rates the interaction as minor. Bazedoxifene-conjugated estrogens and Folic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral estrogens have been linked to modestly lower folate levels in some studies. The effect is small and rarely causes deficiency.
How serious is the interaction between Bazedoxifene-conjugated estrogens and Folic acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is required; assess folate status only if deficiency is suspected.
What other medicines interact with Bazedoxifene-conjugated estrogens?
MediHelp also lists interactions of Bazedoxifene-conjugated estrogens with, for example, Anastrozole, Ospemifene, Antithrombin alfa. The full list is on the Bazedoxifene-conjugated estrogens page.
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