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Drug interactions

Bazedoxifene / conjugated estrogens + Penicillin g

Severity: Minor

Bazedoxifene / conjugated estrogens and Penicillin g: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Reduced estrogen recycling from altered gut flora has been proposed for antibiotics, but evidence of clinically significant loss of effect is lacking for non-rifamycin antibiotics. The risk to menopausal therapy efficacy is low.

What this interaction means in plain words

Bazedoxifene / conjugated estrogens and Penicillin g have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical reduction of enterohepatic recirculation of estrogens through altered intestinal flora.

What to do

No action is generally required; report breakthrough bleeding or return of vasomotor symptoms.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Bazedoxifene / conjugated estrogens with Penicillin g?

MediHelp rates the interaction as minor. Bazedoxifene / conjugated estrogens and Penicillin g have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reduced estrogen recycling from altered gut flora has been proposed for antibiotics, but evidence of clinically significant loss of effect is lacking for non-rifamycin antibiotics. The risk to menopausal therapy efficacy is low.

How serious is the interaction between Bazedoxifene / conjugated estrogens and Penicillin g?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is generally required; report breakthrough bleeding or return of vasomotor symptoms.

What other medicines interact with Penicillin g?

MediHelp also lists interactions of Penicillin g with, for example, Amifampridine, Amiloride, Bcg vaccine live. The full list is on the Penicillin g page.

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