Drug interactions
Bcg vaccine live + Chloroquine
Severity: Minor
Bcg vaccine live and Chloroquine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine may reduce the immune response to some live vaccines. There is little evidence for BCG, and the interaction is largely theoretical.
What this interaction means in plain words
Bcg vaccine live and Chloroquine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible immunomodulatory effects of chloroquine; the mechanism is not established.
What to do
No specific action is needed. Where practical, give BCG before starting prolonged chloroquine.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Bcg vaccine live with Chloroquine?
MediHelp rates the interaction as minor. Bcg vaccine live and Chloroquine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chloroquine may reduce the immune response to some live vaccines. There is little evidence for BCG, and the interaction is largely theoretical.
How serious is the interaction between Bcg vaccine live and Chloroquine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed. Where practical, give BCG before starting prolonged chloroquine.
What other medicines interact with Chloroquine?
MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.
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