Drug interactions
Golimumab + Measles mumps and rubella vaccine live
Severity: Contraindicated
Golimumab and Measles mumps and rubella vaccine live: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
MMR is a live attenuated vaccine, and immunosuppression from golimumab may allow vaccine virus to replicate and cause illness. Vaccine efficacy may also be reduced.
What this interaction means in plain words
Golimumab and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Why it happens
TNF-alpha blockade impairs immune control of replicating live attenuated viruses.
What to do
Do not administer during golimumab therapy; complete live vaccination before starting treatment when possible and observe guideline-recommended intervals after discontinuation.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
- Golimumab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Golimumab with Measles mumps and rubella vaccine live?
MediHelp rates the interaction as contraindicated. Golimumab and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMR is a live attenuated vaccine, and immunosuppression from golimumab may allow vaccine virus to replicate and cause illness. Vaccine efficacy may also be reduced.
How serious is the interaction between Golimumab and Measles mumps and rubella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer during golimumab therapy; complete live vaccination before starting treatment when possible and observe guideline-recommended intervals after discontinuation.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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