Drug interactions
Belimumab + Oxaliplatin
Severity: Moderate
Belimumab and Oxaliplatin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can impair immune defenses. Using them together may increase the risk of serious infections.
What this interaction means in plain words
Belimumab and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Belimumab belongs to Miscellaneous; Oxaliplatin belongs to Oncology.
Why it happens
Additive immunosuppression (cytotoxic myelosuppression plus B-cell survival inhibition).
What to do
Monitor for signs of infection and blood counts. Treat infections promptly and consider delaying belimumab during active infection.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Contraindicated
- Bcg vaccine live + Oxaliplatin Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine live + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine + Oxaliplatin Contraindicated
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Contraindicated
Other interactions of Belimumab
- Belimumab + Measles mumps and rubella vaccine Major
- Abatacept + Belimumab Moderate
- Adalimumab + Belimumab Moderate
- Anakinra + Belimumab Moderate
- Anti-thymocyte + Belimumab Moderate
- Belimumab + Denosumab Moderate
Frequently asked questions
Can I take Belimumab with Oxaliplatin?
MediHelp rates the interaction as moderate. Belimumab and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents can impair immune defenses. Using them together may increase the risk of serious infections.
How serious is the interaction between Belimumab and Oxaliplatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of infection and blood counts. Treat infections promptly and consider delaying belimumab during active infection.
What other medicines interact with Oxaliplatin?
MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.
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