Drug interactions
Benazepril + Paclitaxel
Severity: Minor
Benazepril and Paclitaxel: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Paclitaxel infusions can cause hypotension, often linked to hypersensitivity reactions or the infusion vehicle. Benazepril may add to the blood pressure drop, although a direct interaction is not well established.
What this interaction means in plain words
Benazepril and Paclitaxel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Benazepril belongs to Cardiovascular; Paclitaxel belongs to Oncology.
Why it happens
Possible additive hypotension; no specific pharmacokinetic mechanism is established.
What to do
Monitor blood pressure during paclitaxel infusions and consider holding the ACE inhibitor on infusion days if the patient becomes hypotensive.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Other interactions of Paclitaxel
Frequently asked questions
Can I take Benazepril with Paclitaxel?
MediHelp rates the interaction as minor. Benazepril and Paclitaxel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Paclitaxel infusions can cause hypotension, often linked to hypersensitivity reactions or the infusion vehicle. Benazepril may add to the blood pressure drop, although a direct interaction is not well established.
How serious is the interaction between Benazepril and Paclitaxel?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during paclitaxel infusions and consider holding the ACE inhibitor on infusion days if the patient becomes hypotensive.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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