Drug interactions
Benazepril + Tamsulosin
Severity: Minor
Benazepril and Tamsulosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tamsulosin and ACE inhibitors both lower blood pressure, so combined use may increase orthostatic hypotension, especially after the first doses. Elderly or volume-depleted patients are most susceptible.
What this interaction means in plain words
Benazepril and Tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Benazepril belongs to Cardiovascular; Tamsulosin belongs to Genitourinary.
Why it happens
Additive hypotension from alpha-1 adrenergic blockade and ACE inhibition.
What to do
Check orthostatic blood pressure after starting or adjusting either drug and advise slow position changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tamsulosin
- Alfuzosin + Tamsulosin Major
- Avanafil + Tamsulosin Major
- Ceritinib + Tamsulosin Major
- Clarithromycin + Tamsulosin Major
- Cobicistat + Tamsulosin Major
- Doxazosin + Tamsulosin Major
Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Frequently asked questions
Can I take Benazepril with Tamsulosin?
MediHelp rates the interaction as minor. Benazepril and Tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tamsulosin and ACE inhibitors both lower blood pressure, so combined use may increase orthostatic hypotension, especially after the first doses. Elderly or volume-depleted patients are most susceptible.
How serious is the interaction between Benazepril and Tamsulosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check orthostatic blood pressure after starting or adjusting either drug and advise slow position changes.
What other medicines interact with Tamsulosin?
MediHelp also lists interactions of Tamsulosin with, for example, Alfuzosin, Avanafil, Ceritinib. The full list is on the Tamsulosin page.
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