Drug interactions
Bendroflumethiazide + Miglitol
Severity: Minor
Bendroflumethiazide and Miglitol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazide diuretics can raise blood glucose and reduce the effectiveness of antidiabetic drugs. In patients on miglitol, glycemic control may worsen, mainly with higher thiazide doses.
What this interaction means in plain words
Bendroflumethiazide and Miglitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Thiazides impair insulin secretion and sensitivity, in part via hypokalemia, opposing the glucose-lowering effect of miglitol.
What to do
Monitor blood glucose and potassium when a thiazide is started or its dose increased. Adjust antidiabetic therapy if control deteriorates.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Miglitol
- Miglitol + Pramlintide Major
- Aripiprazole + Miglitol Moderate
- Asenapine + Miglitol Moderate
- Chlorthalidone + Miglitol Moderate
- Clozapine + Miglitol Moderate
- Cortisone + Miglitol Moderate
Frequently asked questions
Can I take Bendroflumethiazide with Miglitol?
MediHelp rates the interaction as minor. Bendroflumethiazide and Miglitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazide diuretics can raise blood glucose and reduce the effectiveness of antidiabetic drugs. In patients on miglitol, glycemic control may worsen, mainly with higher thiazide doses.
How serious is the interaction between Bendroflumethiazide and Miglitol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and potassium when a thiazide is started or its dose increased. Adjust antidiabetic therapy if control deteriorates.
What other medicines interact with Miglitol?
MediHelp also lists interactions of Miglitol with, for example, Pramlintide, Aripiprazole, Asenapine. The full list is on the Miglitol page.
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