Drug interactions
Aripiprazole + Miglitol
Severity: Moderate
Aripiprazole and Miglitol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aripiprazole may cause hyperglycemia in some patients, which can reduce the effectiveness of antidiabetic therapy such as miglitol. The effect is variable and generally less pronounced than with some other antipsychotics.
What this interaction means in plain words
Aripiprazole and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aripiprazole belongs to Central Nervous System; Miglitol belongs to Endocrine.
Why it happens
Pharmacodynamic antagonism, as atypical antipsychotics can impair glucose regulation.
What to do
Monitor blood glucose and HbA1c when aripiprazole is started or adjusted. Intensify the antidiabetic regimen if control worsens.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Other interactions of Miglitol
- Miglitol + Pramlintide Major
- Asenapine + Miglitol Moderate
- Chlorthalidone + Miglitol Moderate
- Clozapine + Miglitol Moderate
- Cortisone + Miglitol Moderate
- Darunavir + Miglitol Moderate
Frequently asked questions
Can I take Aripiprazole with Miglitol?
MediHelp rates the interaction as moderate. Aripiprazole and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aripiprazole may cause hyperglycemia in some patients, which can reduce the effectiveness of antidiabetic therapy such as miglitol. The effect is variable and generally less pronounced than with some other antipsychotics.
How serious is the interaction between Aripiprazole and Miglitol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c when aripiprazole is started or adjusted. Intensify the antidiabetic regimen if control worsens.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
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