Drug interactions
Cortisone + Miglitol
Severity: Moderate
Cortisone and Miglitol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroids raise blood glucose and can reduce the effectiveness of antidiabetic therapy. Patients taking miglitol may see worse glycemic control, especially with prolonged or high-dose use.
What this interaction means in plain words
Cortisone and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Corticosteroids increase hepatic gluconeogenesis and insulin resistance, opposing the glucose-lowering effect of miglitol.
What to do
Monitor blood glucose, particularly postprandial values, during corticosteroid therapy. Increase antidiabetic therapy as needed and reduce it again when the steroid is tapered.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Miglitol
- Miglitol + Pramlintide Major
- Aripiprazole + Miglitol Moderate
- Asenapine + Miglitol Moderate
- Chlorthalidone + Miglitol Moderate
- Clozapine + Miglitol Moderate
- Darunavir + Miglitol Moderate
Frequently asked questions
Can I take Cortisone with Miglitol?
MediHelp rates the interaction as moderate. Cortisone and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids raise blood glucose and can reduce the effectiveness of antidiabetic therapy. Patients taking miglitol may see worse glycemic control, especially with prolonged or high-dose use.
How serious is the interaction between Cortisone and Miglitol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose, particularly postprandial values, during corticosteroid therapy. Increase antidiabetic therapy as needed and reduce it again when the steroid is tapered.
What other medicines interact with Miglitol?
MediHelp also lists interactions of Miglitol with, for example, Pramlintide, Aripiprazole, Asenapine. The full list is on the Miglitol page.
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