Drug interactions
Benperidol + Dantrolene
Severity: Moderate
Benperidol and Dantrolene: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Benperidol is a sedating butyrophenone antipsychotic, and dantrolene causes drowsiness. Together they may increase sedation and impair coordination.
What this interaction means in plain words
Benperidol and Dantrolene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive central nervous system depressant effects.
What to do
Monitor for oversedation and falls, particularly in older patients. Adjust doses if drowsiness interferes with daily function.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dantrolene
Frequently asked questions
Can I take Benperidol with Dantrolene?
MediHelp rates the interaction as moderate. Benperidol and Dantrolene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Benperidol is a sedating butyrophenone antipsychotic, and dantrolene causes drowsiness. Together they may increase sedation and impair coordination.
How serious is the interaction between Benperidol and Dantrolene?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for oversedation and falls, particularly in older patients. Adjust doses if drowsiness interferes with daily function.
What other medicines interact with Dantrolene?
MediHelp also lists interactions of Dantrolene with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant. The full list is on the Dantrolene page.
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