Drug interactions
Betaxolol + Hydrochlorothiazide-irbesartan
Severity: Minor
Betaxolol and Hydrochlorothiazide-irbesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Betaxolol with irbesartan and hydrochlorothiazide produces additive blood pressure lowering, which may be intended but can cause hypotension or bradycardia. Thiazide-related changes in potassium are the main metabolic consideration.
What this interaction means in plain words
Betaxolol and Hydrochlorothiazide-irbesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Betaxolol belongs to Cardiovascular; Hydrochlorothiazide-irbesartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects of beta blockade, angiotensin receptor blockade and diuresis.
What to do
Monitor blood pressure and heart rate when starting or adjusting doses. Check potassium periodically.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-irbesartan
- Aliskiren + Hydrochlorothiazide-irbesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-irbesartan Contraindicated
- Hydrochlorothiazide-irbesartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-irbesartan Major
- Amifostine + Hydrochlorothiazide-irbesartan Major
- Amiloride + Hydrochlorothiazide-irbesartan Major
Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Betaxolol with Hydrochlorothiazide-irbesartan?
MediHelp rates the interaction as minor. Betaxolol and Hydrochlorothiazide-irbesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Betaxolol with irbesartan and hydrochlorothiazide produces additive blood pressure lowering, which may be intended but can cause hypotension or bradycardia. Thiazide-related changes in potassium are the main metabolic consideration.
How serious is the interaction between Betaxolol and Hydrochlorothiazide-irbesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting doses. Check potassium periodically.
What other medicines interact with Hydrochlorothiazide-irbesartan?
MediHelp also lists interactions of Hydrochlorothiazide-irbesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-irbesartan page.
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