Drug interactions
Bethanechol + Cyclizine
Severity: Minor
Bethanechol and Cyclizine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cyclizine has anticholinergic properties that may counteract bethanechol's muscarinic stimulation of bladder and gut. The effect is usually modest at standard doses.
What this interaction means in plain words
Bethanechol and Cyclizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bethanechol belongs to Gastrointestinal Tract; Cyclizine belongs to Respiratory.
Why it happens
Antimuscarinic activity of cyclizine opposes bethanechol at muscarinic receptors.
What to do
Monitor for reduced bethanechol effect on bladder emptying; choose a non-anticholinergic antiemetic if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bethanechol
- Bethanechol + Darifenacin Major
- Bethanechol + Fesoterodine Major
- Bethanechol + Oxybutynin Major
- Bethanechol + Physostigmine Major
- Amifampridine + Bethanechol Moderate
- Amitriptyline + Bethanechol Moderate
Other interactions of Cyclizine
- Calcium / magnesium / potassium / sodium oxybates + Cyclizine Major
- Cyclizine + Henbane Major
- Cyclizine + Sodium oxybate Major
- Abobotulinumtoxina + Cyclizine Moderate
- Alfentanil + Cyclizine Moderate
- Alprazolam + Cyclizine Moderate
Frequently asked questions
Can I take Bethanechol with Cyclizine?
MediHelp rates the interaction as minor. Bethanechol and Cyclizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cyclizine has anticholinergic properties that may counteract bethanechol's muscarinic stimulation of bladder and gut. The effect is usually modest at standard doses.
How serious is the interaction between Bethanechol and Cyclizine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced bethanechol effect on bladder emptying; choose a non-anticholinergic antiemetic if needed.
What other medicines interact with Bethanechol?
MediHelp also lists interactions of Bethanechol with, for example, Darifenacin, Fesoterodine, Oxybutynin. The full list is on the Bethanechol page.
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