Drug interactions
Bethanechol + Flavoxate
Severity: Moderate
Bethanechol and Flavoxate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Flavoxate has antispasmodic and mild anticholinergic properties on the urinary tract that may counteract bethanechol. The clinical effect is generally modest.
What this interaction means in plain words
Bethanechol and Flavoxate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bethanechol belongs to Gastrointestinal Tract; Flavoxate belongs to Genitourinary.
Why it happens
Smooth muscle relaxation and weak antimuscarinic activity oppose bethanechol's stimulation.
What to do
Avoid using the two for the same bladder indication; monitor voiding if both are given.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bethanechol
- Bethanechol + Darifenacin Major
- Bethanechol + Fesoterodine Major
- Bethanechol + Oxybutynin Major
- Bethanechol + Physostigmine Major
- Amifampridine + Bethanechol Moderate
- Amitriptyline + Bethanechol Moderate
Other interactions of Flavoxate
- Clozapine + Flavoxate Major
- Abobotulinumtoxina + Flavoxate Moderate
- Aclidinium + Flavoxate Moderate
- Amantadine + Flavoxate Moderate
- Amitriptyline + Flavoxate Moderate
- Amoxapine + Flavoxate Moderate
Frequently asked questions
Can I take Bethanechol with Flavoxate?
MediHelp rates the interaction as moderate. Bethanechol and Flavoxate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Flavoxate has antispasmodic and mild anticholinergic properties on the urinary tract that may counteract bethanechol. The clinical effect is generally modest.
How serious is the interaction between Bethanechol and Flavoxate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using the two for the same bladder indication; monitor voiding if both are given.
What other medicines interact with Bethanechol?
MediHelp also lists interactions of Bethanechol with, for example, Darifenacin, Fesoterodine, Oxybutynin. The full list is on the Bethanechol page.
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