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Drug interactions

Bevacizumab + Ublituximab

Severity: Minor

Bevacizumab and Ublituximab: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Ublituximab depletes B cells and causes sustained immunosuppression, while bevacizumab impairs wound healing and has a limited effect on immune function. Together they could modestly raise infection risk, but a meaningful additive immunosuppressive interaction has not been well established.

What this interaction means in plain words

Bevacizumab and Ublituximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Bevacizumab belongs to Oncology; Ublituximab belongs to Miscellaneous.

Evidence level: Low

Why it happens

Theoretical additive effects on infection risk; bevacizumab is not a significant immunosuppressant, so the mechanism is not firmly established.

What to do

Monitor for infections and delay elective procedures in patients on bevacizumab because of wound-healing impairment. Screen for hepatitis B before ublituximab as labeled.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Bevacizumab with Ublituximab?

MediHelp rates the interaction as minor. Bevacizumab and Ublituximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ublituximab depletes B cells and causes sustained immunosuppression, while bevacizumab impairs wound healing and has a limited effect on immune function. Together they could modestly raise infection risk, but a meaningful additive immunosuppressive interaction has not been well established.

How serious is the interaction between Bevacizumab and Ublituximab?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for infections and delay elective procedures in patients on bevacizumab because of wound-healing impairment. Screen for hepatitis B before ublituximab as labeled.

What other medicines interact with Bevacizumab?

MediHelp also lists interactions of Bevacizumab with, for example, Sunitinib, Daunorubicin, Dengue vaccine. The full list is on the Bevacizumab page.

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