Drug interactions
Bexarotene + Saxagliptin
Severity: Minor
Bexarotene and Saxagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bexarotene may enhance insulin sensitivity, so combining it with antidiabetic drugs could increase glucose-lowering effects. Hypoglycemia with saxagliptin alone is unlikely but possible with other agents.
What this interaction means in plain words
Bexarotene and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bexarotene belongs to Oncology; Saxagliptin belongs to Endocrine.
Why it happens
Possible additive insulin-sensitizing effect of bexarotene; mechanism not well established.
What to do
Monitor blood glucose when starting bexarotene and adjust other antidiabetic drugs if lows occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Saxagliptin
- Albiglutide + Saxagliptin Moderate
- Amlodipine-benazepril + Saxagliptin Moderate
- Aripiprazole + Saxagliptin Moderate
- Asenapine + Saxagliptin Moderate
- Atazanavir + Saxagliptin Moderate
- Benazepril + Saxagliptin Moderate
Other interactions of Bexarotene
- Bexarotene + Gemfibrozil Major
- Bexarotene + Lorlatinib Major
- Alogliptin-pioglitazone + Bexarotene Moderate
- Amobarbital + Bexarotene Moderate
- Aprepitant + Bexarotene Moderate
- Axitinib + Bexarotene Moderate
Frequently asked questions
Can I take Bexarotene with Saxagliptin?
MediHelp rates the interaction as minor. Bexarotene and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bexarotene may enhance insulin sensitivity, so combining it with antidiabetic drugs could increase glucose-lowering effects. Hypoglycemia with saxagliptin alone is unlikely but possible with other agents.
How serious is the interaction between Bexarotene and Saxagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting bexarotene and adjust other antidiabetic drugs if lows occur.
What other medicines interact with Saxagliptin?
MediHelp also lists interactions of Saxagliptin with, for example, Albiglutide, Amlodipine-benazepril, Aripiprazole. The full list is on the Saxagliptin page.
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