Drug interactions
Biotin + Neomycin
Severity: Minor
Biotin and Neomycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral neomycin may reduce intestinal bacteria that synthesize biotin. Dietary intake is the main source, so clinically meaningful deficiency is unlikely.
What this interaction means in plain words
Biotin and Neomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Biotin belongs to Gastrointestinal Tract; Neomycin belongs to Anti Bacterial.
Why it happens
Theoretical suppression of biotin-producing gut flora.
What to do
No action is needed for typical short courses. Consider biotin status only with prolonged therapy and poor dietary intake.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Neomycin
- Amikacin + Neomycin Major
- Amphotericin b deoxycholate + Neomycin Major
- Capreomycin + Neomycin Major
- Cidofovir + Neomycin Major
- Colistin + Neomycin Major
- Ethacrynic acid + Neomycin Major
Other interactions of Biotin
- Biotin + Levothyroxine Moderate
- Azithromycin + Biotin Minor
- Biotin + Carbamazepine Minor
- Biotin + Cefalexin Minor
- Biotin + Erythromycin base Minor
- Biotin + Erythromycin ethylsuccinate Minor
Frequently asked questions
Can I take Biotin with Neomycin?
MediHelp rates the interaction as minor. Biotin and Neomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral neomycin may reduce intestinal bacteria that synthesize biotin. Dietary intake is the main source, so clinically meaningful deficiency is unlikely.
How serious is the interaction between Biotin and Neomycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed for typical short courses. Consider biotin status only with prolonged therapy and poor dietary intake.
What other medicines interact with Neomycin?
MediHelp also lists interactions of Neomycin with, for example, Amikacin, Amphotericin b deoxycholate, Capreomycin. The full list is on the Neomycin page.
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