Drug interactions
Bismuth subsalicylate + Esmolol
Severity: Minor
Bismuth subsalicylate and Esmolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Esmolol is given intravenously for short periods in monitored settings, and incidental salicylate from bismuth subsalicylate is unlikely to alter its effect meaningfully. Any interaction is theoretical, through reduced renal prostaglandin synthesis.
What this interaction means in plain words
Bismuth subsalicylate and Esmolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bismuth subsalicylate belongs to Gastrointestinal Tract; Esmolol belongs to Cardiovascular.
Why it happens
Salicylate-related prostaglandin inhibition could theoretically oppose beta-blocker antihypertensive effects.
What to do
No specific action is needed beyond routine blood pressure monitoring during esmolol infusion.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bismuth subsalicylate
- Bismuth subsalicylate + Dichlorphenamide Major
- Bismuth subsalicylate + Warfarin Major
- Acetylsalicylic acid + Bismuth subsalicylate Moderate
- Amlodipine-benazepril + Bismuth subsalicylate Moderate
- Aspirin / citric acid / sodium bicarbonate + Bismuth subsalicylate Moderate
- Aspirin rectal + Bismuth subsalicylate Moderate
Other interactions of Esmolol
- Acebutolol + Esmolol Major
- Amifostine + Esmolol Major
- Amiodarone + Esmolol Major
- Celiprolol + Esmolol Major
- Diltiazem + Esmolol Major
- Epinephrine racemic + Esmolol Major
Frequently asked questions
Can I take Bismuth subsalicylate with Esmolol?
MediHelp rates the interaction as minor. Bismuth subsalicylate and Esmolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Esmolol is given intravenously for short periods in monitored settings, and incidental salicylate from bismuth subsalicylate is unlikely to alter its effect meaningfully. Any interaction is theoretical, through reduced renal prostaglandin synthesis.
How serious is the interaction between Bismuth subsalicylate and Esmolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond routine blood pressure monitoring during esmolol infusion.
What other medicines interact with Bismuth subsalicylate?
MediHelp also lists interactions of Bismuth subsalicylate with, for example, Dichlorphenamide, Warfarin, Acetylsalicylic acid. The full list is on the Bismuth subsalicylate page.
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